Survival and complications of full-arch polyether-ether-ketone frameworks in implant-supported All-on-X prostheses
A systematic review
DOI:
https://doi.org/10.56162/transdigital616Keywords:
Polyether-ether-ketone, implant-supported prostheses, full arch rehabilitation, All-on-X, prosthetic complications.Abstract
Prosthetic complications in All-on-X restorations are related to the material of the framework. Polyether ether ketone (PEEK) is an innovative alternative, but its clinical performance has not yet been established. Therefore, the aims of this study was to analyze the clinical survival and prosthetic complications associated with the use of PEEK frameworks in All-on-X implant-supported prostheses through a systematic review. The systematic review was conducted in four phases and included scientific publications on this topic that met the established inclusion and exclusion criteria. The results demonstrated that there are few clinical studies on prosthetic or implant follow-up, of which in vitro or Finite Element Analysis (FEA) studies are the most common. Likewise, most clinical studies showed implant survival rates between 98% and 100%, while prosthetic survival ranged from 93% to 100%. On the other hand, the most common complications were loosening of prosthetic screws, prosthetic fractures, and adhesion failures. In conclusion, it was determined that although PEEK represents a potential alternative for frameworks in implant-supported full-arch restorations, the available evidence is dominated by experimental studies and presents consistent results. More longitudinal clinical studies are needed to establish its actual performance under functional conditions.
References
Abou-Ayash, S., Schimmel, M., Özcan, M., Ozcelik, B., Brägger, U., & Yilmaz, B. (2021). Trueness and marginal fit of implant-supported complete-arch fixed prosthesis frameworks made of high-performance polymers and titanium: An explorative in-vitro study. Journal of Dentistry, 113(103784).
Abouelhuda, M. M., Ibrahim, A. M., Elkenawy, M. H., & Hegazy, S. A. E. (2025). Maxillary All-on-6 treatment using zygomatic implants. Bone loss evaluation by CBCT: 3-year follow-up. International Journal of Prosthodontics, 38(1), 46-54. https://doi.org/10.11607/ijp.8744
Almjaddr, M., & Saker, J. (2024). Effect of different cantilever lengths in polyether ether ketone prosthetic framework in All-on-four technique on stress distribution: A three-dimensional (3D) finite element analysis. Cureus, 16(11), e74544. https://doi.org/10.7759/cureus.74544
Azhar, I. S. (2023). Polyether ether ketones (PEEK): Properties and potential applications in dental implantology. Journal of Implant and Oral Health, 10(4), 245-253. https://doi.org/10.4103/jioh.jioh_10_22
Blanch-Martínez, N., Arias-Herrera, S., & Martínez-González, A. (2021). Behavior of polyether-ether-ketone (PEEK) in prostheses on dental implants: A review. Journal of Clinical and Experimental Dentistry, 13(5), e520-e526. https://doi.org/10.4317/jced.58102
Cabbarova, L., Tunçdemir, A. R., & Mohammadi, R. (2026). Biomechanical evaluation of framework materials in All-on-four versus All-on-six prostheses: A finite element study. Clinical and Experimental Dental Research, 12(1), e70277. https://doi.org/10.1002/cre2.70277
Chen, X., Xu, Z., Gai, K., Pei, X., Li, R., & Wan, Q. (2025). Biomechanical analysis of All-on-4 implant supported framework using different materials across various clinical practice. BMC Oral Health, 25(1), 552.
Dayan, S. C., & Geckili, O. (2021). The influence of framework material on stress distribution in maxillary complete-arch fixed prostheses supported by four dental implants: A three-dimensional finite element analysis. Computer Methods in Biomechanics and Biomedical Engineering, 24(14), 1606-1617.
De Araújo Nobre, M., Moura Guedes, C., Almeida, R., Silva, A., & Sereno, N. (2020). Hybrid polyetheretherketone (PEEK)–acrylic resin prostheses and the All-on-4 concept: A full-arch implant-supported fixed solution with 3 years of follow-up. Journal of Clinical Medicine, 9(7), 2187.
De Araújo Nobre, M., Moura Guedes, C., Almeida, R., Silva, A., & Sereno, N. (2023). The All-on-4 concept using polyetheretherketone (PEEK)-acrylic resin prostheses: Follow-up results of the development group at 5 years and the routine group at one year. Biomedicines, 11(11), 3013.
Eraslan, R., Colpak, E. D., Kilic, K., & Polat, Z. A. (2021). Biomechanical properties and biocompatibility of implant-supported full arch fixed prosthesis substructural materials. Nigerian Journal of Clinical Practice, 24(9), 1373-1379. https://doi.org/10.4103/njcp.njcp_666_20
Gürkan, M., Kumbuloglu, O., ?ahan, M. H., Narin, M., Kanda?, H., Arman, Y., Yildiz, H., & Pekedis, M. (2025). Biomechanics of the implant-supported full arch fixed complete denture manufactured by milling and injection techniques: An experimental and FEA study. Journal of Prosthodontics, 1-11.
Haji Bakr, H., & Kazazo?lu, E. (2026). In vitro evaluation of wear characteristics in complete arch implant-supported fixed dental prostheses: Impact of framework–veneer material combinations and compatibility. The Journal of Prosthetic Dentistry. https://doi.org/10.1016/j.prosdent.2025.12.041
Jung, B-Y., Park, W-S., Woo, C-W., & Jeong, S. A. (2023). Zirconia-veneered polyetherketoneketone frameworks of implant-supported complete arch fixed dental prostheses: A report on 5 patients. The Journal of Prosthetic Dentistry, 130(4), 419-433. https://doi.org/10.1016/j.prosdent.2022.07.013
Kilic, S., & Caglar, I. (2025). Investigation of stress distribution between two different implant concepts in implant-supported maxillary prostheses with different framework materials: A finite element study. International Journal of Prosthodontics, 38(3), 331-338.
Kortam, S. A., ELsyad, M. A., Awad, S. S., & ElHelbawy, N. E. (2022). Metal-ceramic and polyether ether ketone-composite maxillary fixed prosthesis supported by four implants and opposed by removable distal extension partial dentures: A comparative study of clinical and prosthetic outcomes. The International Journal of Oral & Maxillofacial Implants, 37(1), 181-189.
Lan, Y., & Su, B. (2025). Dynamic finite element analysis of stress distribution in edentulous fixed restorations: Effects of different implant configurations and framework materials. Journal of Stomatology, Oral and Maxillofacial Surgery, 127(1), 102647.
Maló, P., De Araújo Nobre, M., Moura Guedes, C., Almeida, R., Silva, A., Sereno, N., & Legatheaux, J. (2018). Short-term report of an ongoing prospective cohort study evaluating the outcome of full-arch implant-supported fixed hybrid polyetheretherketone-acrylic resin prostheses and the All-on-Four concept. Clinical Implant Dentistry and Related Research, 20(5), 692-702.
Mendes Tribst, J. P., Campanelli de Morais, D., Melo de Matos, J. D., Lopes, G. D. R. S., Dal Piva, A. M. O., Souto Borges, A. L., Bottino, M. A., Lanzzoti, A., Martorelli, M., & Ausiello, P. (2022). Influence of framework material and posterior implant angulation in full-arch All-on-4 implant-supported prosthesis stress concentration. Dentistry Journal, 10(1),12.
Messias, A., Neto, M. A., Piedade, A. P., Amaro, A., Krauser, J. T., & Guerra, F. (2025). Comparison of surface strains of polymeric frameworks for fixed implant-supported prostheses: A digital image correlation study. Materials, 18(8), 1700.
Mishra, S. K., Prasad, K., & Kumar, A. (2023). Complete-arch implant-supported fixed dental prostheses with PEEK frameworks: Systematic review of clinical studies. International Journal of Prosthodontics, 24(193).
Montero, J., Guadilla, Y., Flores, J., Pardal-Peláez, B., Quispe-López, N., Gómez-Polo, C., & Dib, A. (2021). Patient-centered treatment outcomes with full-arch PEEK rehabilitation supported on four immediate or conventionally loaded implants: A randomized clinical trial. Journal of Clinical Medicine, 10(19), 4589.
Mourad, K. E., Altonbary, G. Y., Emera, R. M. K., & Hegazy, S. A. F. (2023). Polyetheretherketone computer-aided design and computer-aided manufacturing framework for All-on-Four mandibular full-arch prosthesis: 3 years' retrospective study of peri-implant soft tissue changes and ridge base relationship. Journal of Prosthodontics, 32(7), 579-587.
Mourad, K. E., Rashed, N. H. A. H., Altonbary, G. Y., & Fattah Hegazy, S. A. (2024). Five years of radiographic evaluation for the peri-implant bone changes of all-on-four implant prostheses constructed from different framework materials using different digital construction techniques. BMC Oral Health, 24(1), 910.
Nellissery, A., Mamorsky, M., & Goodenough, M. (2022). Implant success rates in the All-on-X treatment concept as compared to the All-on-4 concept: A retrospective case series. Journal of Oral and Maxillofacial Surgery, 80(9), S68-S69.
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo?Wilson, E., McDonald, S., … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372(71). https://doi.org/10.1136/bmj.n71
Papathanasiou, I., Kamposiora, P., Papavasiliou, G., & Ferrari, M. (2020). The use of PEEK in digital prosthodontics: A narrative review. BMC Oral Health, 20(1), 217.
Sacks, G., Shah, V., Yao, L., Yan, C., Shah, D., Limeta, L., & DeStefano, V. (2024). Polyaryletherketones: Properties and applications in modern medicine. Biomedical Technology, 6, 75-89.
Sánchez-Meca, J., & Botella, J. (2010). Revisiones sistemáticas y metaanálisis: Herramientas para la práctica profesional. Papeles del Psicólogo, 31(1), 7-17. https://www.papelesdelpsicologo.es/pdf/1792.pdf
Shash, Y. H., El-Wakad, M. T., Eldosoky, M. A. A., & Dohiem, M. M. (2024). Finite element analysis of the effect of framework material and thickness on the biomechanical performance of 'All-on-Four' full-arch prosthesis. Computer Methods in Biomechanics and Biomedical Engineering.
Topcu, E. M., & Mumcu, E. (2022). Biomechanical investigation of maxillary implant-supported full-arch prostheses produced with different framework materials: a finite elements study. Journal of Advanced Prosthodontics, 14(6), 346–359. https://doi.org/10.4047/jap.2022.14.6.346
Vaitiek?nas, I., Klimenko, J., Ivanauskien?, E., & Žilinskas, J. (2020). Stress in the bone and prosthetic components due to “All-on-4” system with polyether-ether-ketone screwing prosthesis: Analysis using 3D finite element method. Stomatologija, Baltic Dental and Maxillofacial Journal, 22(4), 125-128. https://sbdmj.com/204-05.pdf
Villefort, R. F., Santos Diamantino, R., Ventorin von Zeider, S., Souto Borges, A., Silva-Concílio, L. R., Anzaloni Saavedra, S. G., & Mendes Tribsts, J. P. (2021). Mechanical Response of PEKK and PEEK As Frameworks for Implant-Supported Full-Arch Fixed Dental Prosthesis: 3D Finite Element Analysis. European Journal Dentistry, 16(1), 115–121. https://doi.org/10.1055/s-0041-1731833
Vinodh, S., Jingade, R. R. K., Ajjikuttira, P. A., Kyathappa, P., Nataraj, M., & Chalana, B. O. (2023). Comparative evaluation to study the effect of implant support on complete fixed dental prosthesis fabricated with PEEK framework when implants placed in all-on-4 and all-on-6 situation, by strain gauge analysis and finite element analysis - An in vitro study. The Journal of Indian Prosthodontic Society, 23(4), 373-378. https://doi.org/10.4103/jips.jips_196_23
Wang, B., Huang, M., Dang, P., Xie, J., Zhang, X., & Yan, X. (2022). PEEK in fixed dental prostheses: Application and adhesion improvement. Polymers, 14(12), 2323. https://doi.org/10.3390/polym14122323
Yu, W., Li, X., Ma, X., & Xu, X. (2022). Biomechanical analysis of inclined and cantilever design with different implant framework materials in mandibular complete-arch implant restorations. The Journal of Prosthetic Dentistry, 127(5), 783.e1-783.e10. https://doi.org/10.1016/j.prosdent.2022.02.018
Zaki Mohamed, L., Tarek Mohamed, H. T., Eid, H. I., Saeid, S., Elshora, A. A., & El-Hakim, I. E. (2025). Finite element analysis of welded titanium bar and poly ether ether ketone bar in maxillary full arch splinted interim prosthesis. Scientific Reports, 15(6450). https://doi.org/10.1038/s41598-025-99750-x
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